Author

S. M. Gopalakrishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:human· 1

Frequent Co-Authors

A. J. Radosevich· 2 shared F. Pu· 2 shared J. D. Williams· 2 shared N. L. Elsen· 2 shared A. N. Joignant· 1 shared B. G. Bruckner· 1 shared D. A. Fontaine· 1 shared J. W. Sawicki· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. J. Radosevich

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2 papers

Recent·Most cited

Metabolite Fingerprinting for Phenotypic Screening by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

A. N. Joignant, F. Pu, S. M. McLoughlin, J. W. Sawicki, A. J. Radosevich, R. Ma, J. D. Williams, S. M. Gopalakrishnan, N. L. Elsen

This paper demonstrates a high-throughput phenotypic screening method using IR-MALDESI mass spectrometry to identify glutaminase inhibitors and distinguish them from nuisance compounds.

bioRxiv · Dec 20, 2023Cell Biology

A New Platform for Label-Free, Proximal Cellular Pharmacodynamic Assays: Identification of Glutaminase Inhibitors Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

F. Pu, A. J. Radosevich, B. G. Bruckner, D. A. Fontaine, S. C. Panchal, J. D. Williams, S. M. Gopalakrishnan, N. L. Elsen

This paper introduces a high-throughput label-free cellular pharmacodynamic assay using IR-MALDESI to identify glutaminase inhibitors and confirm hits with mass spectrometry-based assays.

bioRxiv · Jan 30, 2023Biochemistry