Author

D. A. Fontaine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. H. de Souza· 1 shared A. J. Radosevich· 1 shared B. G. Bruckner· 1 shared C. R. Kibbe· 1 shared D. B. Davis· 1 shared F. Pu· 1 shared H. T. Kim· 1 shared H. Umhoefer· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. H. de Souza

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Author profile →

2 papers

Recent·Most cited

A New Platform for Label-Free, Proximal Cellular Pharmacodynamic Assays: Identification of Glutaminase Inhibitors Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

F. Pu, A. J. Radosevich, B. G. Bruckner, D. A. Fontaine, S. C. Panchal, J. D. Williams, S. M. Gopalakrishnan, N. L. Elsen

This paper introduces a high-throughput label-free cellular pharmacodynamic assay using IR-MALDESI to identify glutaminase inhibitors and confirm hits with mass spectrometry-based assays.

bioRxiv · Jan 30, 2023Biochemistry

Cholecystokinin Suppresses β-Cell Apoptosis, Including in Human Islets in a Transplant Model

H. T. Kim, A. H. de Souza, H. Umhoefer, J. Han, L. Anzia, S. J. Sacotte, R. A. Williams, J. T. Blumer, J. T. Bartosiak, D. A. Fontaine, M. Baan, C. R. Kibbe, D. B. Davis

This study shows that cholecystokinin reduces β-cell apoptosis in human islets both in vitro and in a transplant model, suggesting its therapeutic potential for diabetes.

bioRxiv · Mar 2, 2021 · PreprintCell Biology