The unfolded protein response triggers the immune deficiency pathway in ticks
L. C. Sidak-Loftis, K. L. Rosche, N. Pence, J. K. Ujczo, J. Hurtado, E. A. Fisk, A. G. Goodman, S. M. Noh, J. W. Peters, D. K. Shaw
The study shows that the unfolded protein response (UPR) initiates the immune deficiency (IMD) pathway in ticks, linking ER stress to pathogen restriction.
bioRxiv · Aug 31, 2021 · PreprintImmunology