CARP2 regulates the Golgi dynamics upon EGF stimulation
This study shows CARP2 regulates Golgi dispersal upon EGF stimulation by ubiquitinating Golgin45.
bioRxiv · Apr 5, 2022 · PreprintCell Biology
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This study shows CARP2 regulates Golgi dispersal upon EGF stimulation by ubiquitinating Golgin45.
bioRxiv · Apr 5, 2022 · PreprintCell Biology
R. Ravindran, A. K. G. Velikkakath, N. D. Narendradev, A. Chandrasekharan, T. R. Santhoshkumar, S. M. Srinivasula
This study shows endosomes facilitate Parkin recruitment to mitochondria, a key step in mitophagy, by interacting with CARP2 before Parkin.
bioRxiv · Feb 19, 2020Cell Biology
P. R. P. Suma, R. A. Padmanabhan, S. R. Telukutla, R. Ravindran, A. K. G. Velikkakath, C. D. Dekiwadia, W. Paul, S. J. Shenoy, M. Laloraya, S. M. Srinivasula, S. V. Bhosale, R. S. Jayasree
This study investigates vanadium pentoxide nanoparticles' effects on triple-negative breast cancer cells, showing time-dependent antioxidant/pro-oxidant properties, lysosomal/mitochondrial accumulation, autophagy induction, and apoptosis, with no observed toxicity in mice.
bioRxiv · Oct 18, 2019 · PreprintScientific Communication & Education
S. V. Nair, N. D. Narendradev, R. P. Nambiar, R. Kumar, S. M. Srinivasula
This study identifies RNF167 and its variants as regulators of lysosomal exocytosis and plasma membrane resealing, with implications for tumor progression.
bioRxiv · Sep 18, 2019Cell Biology