Endosomes facilitate mitochondrial clearance by enhancing Parkin recruitment to mitochondria
R. Ravindran, A. K. G. Velikkakath, N. D. Narendradev, A. Chandrasekharan, T. R. Santhoshkumar, S. M. Srinivasula
This study shows endosomes facilitate Parkin recruitment to mitochondria, a key step in mitophagy, by interacting with CARP2 before Parkin.
bioRxiv · Feb 19, 2020Cell Biology