Secreted filarial nematode galectins modulate host immune cells
H. J. Loghry, N. A. Sondjaja, S. Minkler, M. J. Kimber
This study identifies two secreted galectins from Brugia malayi that modulate host immune cells by polarizing macrophages and inducing Th1 cell apoptosis, contributing to the modified type 2 immune response in chronic lymphatic filariasis.
bioRxiv · May 23, 2022Immunology