Extracellular vesicles secreted by Brugia malayi microfilariae modulate the melanization pathway in the mosquito host
H. J. Loghry, H. Kwon, R. C. Smith, N. A. Sondjaja, S. Minkler, S. Young, N. J. Wheeler, M. Zamanian, L. Bartholomay, M. J. Kimber
This paper shows that extracellular vesicles from Brugia malayi microfilariae reduce melanization in Aedes aegypti mosquitoes by downregulating AAEL002590 and decreasing phenoloxidase activity.
bioRxiv · Apr 11, 2022 · PreprintImmunology