Author

S. Parashuraman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Luini· 4 shared R. Rizzo· 4 shared D. Russo· 3 shared G. D'Angelo· 3 shared I. Agliarulo· 2 shared L. Capolupo· 2 shared M. Pirozzi· 2 shared N. Dathan· 2 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

A. Luini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogene

S. Parashuraman, P. Sahu, F. Russo, I. Agliarulo, R. Rizzo, M. Lo Monte, N. Normanno, S. Soddu, F. Carlomagno, A. Luini

The paper identifies B4GALT5 as a glyco-oncogene by analyzing copy number alterations in glycosylation regulator genes across cancer datasets.

bioRxiv · Mar 30, 2022 · PreprintCancer Biology

Regulated compartmentalization of enzymes in Golgi by GRASP55 controls cellular glycosphingolipid profile and function

P. Pothukuchi, I. Agliarulo, M. Pirozzi, R. Rizzo, D. Russo, G. Turacchio, J. Nuchel, J.-S. Yang, C. J. C. Gehin, L. Capolupo, M. J. Hernandez-Corbacho, A. Biswas, G. Vanacore, N. Dathan, T. Nitta, , S. Parashuraman

This study identifies GRASP55 as a regulator of enzyme compartmentalization in the Golgi, which controls glycosphingolipid biosynthesis and cellular glycan profiles.

bioRxiv · May 3, 2020 · PreprintCell Biology

The Glyco-enzyme adaptor GOLPH3 Links Intra-Golgi Transport Dynamics to Glycosylation Patterns and Cell Proliferation

R. Rizzo, D. Russo, K. Kurokawa, P. Sahu, B. Lombardi, D. Supino, M. Zhukovsky, A. Vocat, P. Pothukuchi, V. Kunnathully, L. Capolupo, G. Boncompain, C. Vitagliano, F. Zito Marino, G. Aquino, , A. Luini

This study shows GOLPH3 regulates glycosylation and cell proliferation by controlling glyco-enzyme recycling and lysosomal degradation.

bioRxiv · Dec 23, 2019 · PreprintCell Biology

Sphingolipid metabolic flow controls phosphoinositide turnover at thetrans Golgi network

S. Capasso, L. Sticco, R. Rizzo, M. Pirozzi, D. Russo, N. Dathan, F. Campelo, J. van Galen, A. Hausser, V. Malhotra, S. Parashuraman, A. Luini, G. D'Angelo

The paper identifies a homeostatic circuit that regulates sphingolipid levels at the trans Golgi network by linking sphingomyelin production to PtdIns(4)P dephosphorylation, which interrupts cholesterol and sphingolipid transport.

bioRxiv · Nov 28, 2016Cell Biology