Author

A. Vocat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

S. T. Cole· 2 shared A. Budillon· 1 shared A. Luini· 1 shared A. Lupien· 1 shared A. Nakano· 1 shared B. Bunk· 1 shared B. Lombardi· 1 shared C. D. Fage· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

S. T. Cole

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis

Y. Dashti, F. Mohammadipanah, M. J. Belousoff, A. Vocat, D. Zabala, C. D. Fage, I. Romero-Canelon, B. Bunk, C. Sproer, J. Overmann, S. T. Cole, G. L. Challis

This study discovers two novel polyglycosylated thiopeptides, persiathiacins A and B, active against drug-resistant tuberculosis and identifies their biosynthetic gene cluster.

bioRxiv · Oct 24, 2021 · PreprintMicrobiology

The Glyco-enzyme adaptor GOLPH3 Links Intra-Golgi Transport Dynamics to Glycosylation Patterns and Cell Proliferation

R. Rizzo, D. Russo, K. Kurokawa, P. Sahu, B. Lombardi, D. Supino, M. Zhukovsky, A. Vocat, P. Pothukuchi, V. Kunnathully, L. Capolupo, G. Boncompain, C. Vitagliano, F. Zito Marino, G. Aquino, , A. Luini

This study shows GOLPH3 regulates glycosylation and cell proliferation by controlling glyco-enzyme recycling and lysosomal degradation.

bioRxiv · Dec 23, 2019 · PreprintCell Biology

Structure-based drug design and characterization of sulfonyl-piperazine benzothiazinone inhibitors of DprE1 from Mycobacterium tuberculosis

J. Piton, A. Vocat, A. Lupien, C. S.-Y. Foo, O. Riabova, V. Makarov, S. T. Cole

The paper designs and characterizes sulfonyl-piperazine benzothiazinone inhibitors of DprE1 from M. tuberculosis, finding they have improved solubility but lower activity than MCZ.

bioRxiv · Apr 10, 2018Pharmacology & Toxicology