Author

S. Pasonen-Seppanen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Varjosalo· 2 shared A. J. Deen· 1 shared A. Poso· 1 shared A.-L. Levonen· 1 shared E. Kansanen· 1 shared E. Moisio· 1 shared H. Jakupovic· 1 shared H. Laitinen· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M. Varjosalo

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Author profile →

2 papers

Recent·Most cited

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

A. J. Deen, S. Adinolfi, J. Harkonen, T. Patinen, X. Liu, T. Laitinen, P. Takabe, K. Kainulainen, S. Pasonen-Seppanen, L. Gawriyski, U. Thanigai Arasu, I. Selvarajan, P. Makinen, H. Laitinen, E. Kansanen, , A.-L. Levonen

This study shows that KEAP1 mutations in lung cancer activate TRAF2-NFκB signaling, enhancing cell survival by preventing apoptosis.

bioRxiv · Oct 10, 2023Cancer Biology

Tissue-ABPP enables high-resolution confocal fluorescence imaging of serine hydrolase activity in cryosections - Application to glioma brain unveils activity hotspots originating from tumor-associated neutrophils

N. Aaltonen, P. Singha, H. Jakupovic, T. Wirth, H. Samaranayake, S. Pasonen-Seppanen, K. Rilla, M. Varjosalo, L. Edgington-Mitchell, P. Kasperkiewicz, M. Drag, S. Kalvala, E. Moisio, J. R. Savinainen, J. T. Laitinen

The paper introduces tissue-ABPP, a method for high-resolution imaging of serine hydrolase activity in tissue sections, revealing activity hotspots in glioma tumors linked to neutrophils.

bioRxiv · Sep 26, 2019Cancer Biology