Author

P. Kasperkiewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Drag· 4 shared T. Janiszewski· 3 shared D. Kaiserman· 2 shared G. Salvesen· 2 shared J. Kulbacka· 2 shared S. Kolt· 2 shared S. S. Snipas· 2 shared A. Gorska· 1 shared

Activity by Year

2019-2019 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

M. Drag

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Noninvasive optical detection of Granzyme B from natural killer cells using enzyme-activated fluorogenic probes

T. Janiszewski, S. Kolt, D. Kaiserman, S. S. Snipas, S. Li, J. Kulbacka, J. Saczko, N. Bovenschen, G. Salvesen, M. Drag, P. Bird, P. Kasperkiewicz

This study develops a fluorogenic probe for detecting Granzyme B activity in natural killer cells and demonstrates its use in analyzing GrB localization and function in cytotoxic cells.

bioRxiv · Dec 16, 2019Biochemistry

Detection of active Granzyme A in NK92 cells with fluorescent activity-based probe

S. Kolt, T. Janiszewski, D. Kaiserman, S. Modrzycka, S. S. Snipas, G. Salvesen, M. Drag, P. I. Bird, P. Kasperkiewicz

The paper develops a fluorescent activity-based probe to detect and track Granzyme A activity in NK92 cells.

bioRxiv · Dec 10, 2019Biochemistry

Tissue-ABPP enables high-resolution confocal fluorescence imaging of serine hydrolase activity in cryosections - Application to glioma brain unveils activity hotspots originating from tumor-associated neutrophils

N. Aaltonen, P. Singha, H. Jakupovic, T. Wirth, H. Samaranayake, S. Pasonen-Seppanen, K. Rilla, M. Varjosalo, L. Edgington-Mitchell, P. Kasperkiewicz, M. Drag, S. Kalvala, E. Moisio, J. R. Savinainen, J. T. Laitinen

The paper introduces tissue-ABPP, a method for high-resolution imaging of serine hydrolase activity in tissue sections, revealing activity hotspots in glioma tumors linked to neutrophils.

bioRxiv · Sep 26, 2019Cancer Biology

Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease

B. M. Babin, P. Kasperkiewicz, T. Janiszewski, E. Yoo, M. Drag, M. Bogyo

The paper uses peptide substrate libraries to determine the specificity of bacterial Lon protease and develops a potent inhibitor that affects Lon function in E. coli without toxicity to mammalian cells.

bioRxiv · Jul 2, 2019Microbiology

The cytoprotective role of antioxidants in mammalian cells under rapidly varying temperature, pressure and UV conditions during stratospheric balloon campaign

J. Kulbacka, D. Przystupski, A. Gorska, P. Rozborska, W. Bartosik, O. Michel, J. Rossowska, A. Szewczyk, M. Drag-Zalesinska, P. Kasperkiewicz, J. Gorski

The paper tests antioxidant compounds' ability to protect human cells from extreme conditions simulated by stratospheric balloon flights.

bioRxiv · Jan 25, 2019Cell Biology