A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production
S. P. Keeler, K. Wu, Y. Zhang, D. Mao, M. Li, C. A. Iberg, S. R. Austin, S. A. Glaser, J. Yantis, S. Podgorny, S. L. Brody, J. R. Chartock, Z. Han, D. E. Byers, A. G. Romero, M. J. Holtzman
This paper develops a potent MAPK13-14 inhibitor, NuP-3, which reduces airway inflammation and mucus production in human airway models and minipig disease models.
bioRxiv · May 26, 2023Immunology