Cancer BiologybioRxivPreprint
Radiation-reprogrammed glioma stem cells generate vascular-like cells to build a trophic niche driving tumor recurrence
S. D. Muthukrishnan, R. Kawaguchi, P. Nair…·H. I. Kornblum
The paper shows radiation induces vascular-like phenotypes in glioma stem cells, creating a trophic niche that promotes tumor recurrence, and identifies P300 inhibition as a potential therapeutic strategy.