ImmunologybioRxivPreprint
FoxP3-mediated blockage of ryanodine receptor 2 is the molecular basis for the contact-based suppression by regulatory T cells
X. Wang, S. Geng, J. Meng…·Y. Shi
This study identifies FoxP3-mediated inhibition of RyR2 as a mechanism by which regulatory T cells suppress immune responses through reduced calcium signaling and impaired T cell-DC interactions.
DOI 10.1101/2022.05.02.490213