N. Kang

Deciphering the Transcription Factor Landscape in Neuroendocrine Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

This study identifies lineage-specific transcription factor profiles in prostate cancer progression, revealing dynamic shifts during NE transdifferentiation and proposing a three-phase model.

PRMT5 deficiency disturbs Nur77 methylation to inhibit endometrial stromal cell differentiation in recurrent implantation failure

This study shows PRMT5 deficiency disrupts Nur77 methylation, impairing endometrial stromal cell differentiation and contributing to recurrent implantation failure.

Polyubiquitinated PCNA promotes alternative lengthening of telomeres by inducing break-induced replication

The paper shows polyubiquitinated PCNA promotes break-induced replication at telomeres and fragile sites by recruiting SLX4, leading to telomere damage and DNA synthesis.

FoxP3-mediated blockage of ryanodine receptor 2 is the molecular basis for the contact-based suppression by regulatory T cells

This study identifies FoxP3-mediated inhibition of RyR2 as a mechanism by which regulatory T cells suppress immune responses through reduced calcium signaling and impaired T cell-DC interactions.

Proteome of actin stress fibers

The paper identifies the proteome of actin stress fibers in human fibroblasts and shows that eEF2 is upregulated with replicative senescence, contributing to SF reinforcement.

Statistical profiling reveals correlations between the cell response to and structural sequence of Rho-GAPs

The paper analyzes the correlation between the morphological response of cells to Rho-GAP silencing and their structural sequence similarity.

Correlation of IL-17 level in gingival crevicular fluid of orthodontically induced inflammatory root resorption

This study measures IL-17 levels in gingival crevicular fluid and correlates them with bone resorption in a rat model of orthodontic treatment.