S. S. Chin

T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling

This study shows that TCR and IL-2 signaling strength during vaccination epigenetically programs memory CD8+ T cell functional fitness through chromatin remodeling.

Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

This study shows that blocking LAG-3 in PD-L1-deficient mice improves blood-stage malaria clearance without relying on humoral immunity.