Author

F. Delahaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

G. Lauvau· 3 shared E. Guillen· 2 shared A. Bauleni· 1 shared A. Buchwald· 1 shared B. Wu· 1 shared C. Koch· 1 shared D. Fooksman· 1 shared D. Zehn· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

G. Lauvau

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling

S. S. Chin, E. Guillen, L. Chorro, S. Achar, S. Oberle, K. Ng, F. Alfei, D. Zehn, G. Altan-Bonnet, F. DELAHAYE, G. Lauvau

This study shows that TCR and IL-2 signaling strength during vaccination epigenetically programs memory CD8+ T cell functional fitness through chromatin remodeling.

bioRxiv · Oct 19, 2021Immunology

Cytolytic memory CD4+ T cell clonotypes are expanded during Plasmodium falciparum infection

R. Furtado, F. Delahaye, J. Zhang, J. Sung, P. Karell, R. S. Kim, S. Caillat-Zucman, L. Liang, P. Felgner, A. Bauleni, S. Gama, A. Buchwald, T. Taylor, K. Seydel, M. Laufer, , G. Lauvau

The paper identifies clonally expanded cytolytic memory CD4+ T cells in Plasmodium falciparum malaria patients and links their reduced chemotactic and inhibitory receptor expression to clinical immunity.

bioRxiv · Jul 21, 2021 · PreprintImmunology

Memory CD8+ T cells mediate early pathogen-specific protection through localized delivery of chemokines and IFNγ to clusters of inflammatory monocytes

M. Boutet, Z. Benet, E. Guillen, C. Koch, S. M. SOUDJA, F. Delahaye, D. Fooksman, G. Lauvau

This study shows memory CD8+ T cells use cognate antigen to rapidly produce chemokines and IFNγ in splenic monocyte clusters, providing early pathogen protection before clonal expansion.

bioRxiv · Mar 1, 2021Immunology

Re-targeting of macroH2A following mitosis to cytogenetic-scale heterochromatic domains

H. Sato, B. Wu, F. Delahaye, R. H. Singer, J. Greally

This study shows that macroH2A re-targets to heterochromatic domains in G1 phase after DNA replication, maintaining epigenetic memory through cell division.

bioRxiv · May 29, 2018Biochemistry