Cell BiologybioRxiv
Mesenchymal Stromal Cells regulate human Hematopoietic Stem Cell survival, engraftment and regeneration via PGE2/cAMP signaling pathway
S. S. N. A. MUDDINENI, C. Katz-Even, A. Zipin-Roitman…·M. Milyavsky
This study shows that mesenchymal stromal cells protect human hematopoietic stem cells from radiation damage via the PGE2/cAMP signaling pathway, enhancing their survival and engraftment.
DOI 10.1038/s41419-026-08502-w