Author

S. S. Smyth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Wu· 2 shared G. Zhang· 2 shared Y. Zhang· 2 shared Z. Li· 2 shared A. Morris· 1 shared A. Pandeya· 1 shared B. Xiang· 1 shared D. Kirchhofer· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

C. Wu

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2 papers

Recent·Most cited

Calcium ion chelation preserves platelet function during cold storage

B. Xiang, G. Zhang, Y. Zhang, C. Wu, S. Joshi, A. Morris, J. Ware, S. S. Smyth, S. W. Whiteheart, Z. Li

This study identifies integrin activation and apoptosis as the mechanism of rapid platelet clearance after cold storage and shows that EGTA treatment enables cold storage of platelets for transfusion.

bioRxiv · Jun 14, 2020Cell Biology

Extracellular histones trigger disseminated intravascular coagulation by lytic cell death

C. Wu, Y. Zhang, L. Li, A. Pandeya, G. Zhang, J. Cui, D. Kirchhofer, J. P. Wood, S. S. Smyth, Y. Wei, Z. Li

The paper shows extracellular histones cause disseminated intravascular coagulation (DIC) via tissue factor-dependent lytic cell death, independent of inflammasome or TLR pathways.

bioRxiv · Jun 11, 2020 · PreprintImmunology