Zinc Metabolic Defect of Aging Alveolar Progenitors in Progressive Pulmonary Fibrosis
J. Liang, G. Huang, X. Liu, F. Taghavifar, N. Liu, Y. Wang, N. Deng, C. Yao, A. Burman, T. Xie, S. Rowan, S. S. Weigt, J. BELPERIO, B. Stripp, W. Parks, , P. Noble
The paper identifies a zinc metabolic defect in alveolar progenitor cells in IPF and aged mice, linked to impaired renewal and fibrosis through ZIP8 downregulation.
bioRxiv · Jul 30, 2020 · PreprintCell Biology