Author

T. Parimon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

P. Chen· 4 shared B. R. Stripp· 2 shared C. M. Hogaboam· 2 shared C. Yao· 2 shared D. Jiang· 2 shared G. Huang· 2 shared P. W. Noble· 2 shared X. Liu· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCell Biology

P. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F)

B. Creyns, B. MacKenzie, Y. Sa, A. L. Coelho, D. Christensen, T. Parimon, B. Windsor, C. M. Hogaboam

This study shows that the CSD peptide LTI-2355 improves phagocytic and reduces pro-inflammatory activity in myeloid cells from IPF and PASC-F patients.

bioRxiv · Dec 1, 2023Immunology

Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19

H. Narasimhan, I. S. Cheon, W. Qian, S. Hu, T. Parimon, C. Zang, P. Chen, J. Sun

This study identifies dysregulated immune-epithelial progenitor interactions in post-viral lung sequelae and shows that targeting IFN-γ, TNF, or IL-1β improves alveolar regeneration and pulmonary function.

bioRxiv · Sep 13, 2023 · PreprintImmunology

Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

O. Burgy, C. H. Mayr, B. Ballester Llobell, A. Sengupta, D. Schenesse, C. Coughlan, T. Parimon, P. Chen, M. Lindner, A. Hilgendorff, M. Mann, A. O. Yildirim, O. Eickelberg, M. Lehmann, H. B. Schiller, , M. Königshoff

This study identifies fibroblast-derived extracellular vesicles containing SFRP1 that contribute to pulmonary fibrosis and suggests SFRP1 as a therapeutic target.

bioRxiv · Dec 22, 2022Cell Biology

Definition and Signatures of Lung Fibroblast Populations in Development and Fibrosis in Mice and Men

X. Liu, S. C. Rowan, J. Liang, C. Yao, G. Huang, N. Deng, T. Xie, D. Wu, Y. Wang, A. Burman, T. Parimon, Z. Borok, P. Chen, W. C. Parks, C. M. Hogaboam, , D. Jiang

This study identifies fibroblast subpopulations in mouse and human lungs using scRNA-seq, revealing conserved transcriptomic signatures and their roles in fibrosis.

bioRxiv · Jul 15, 2020 · PreprintCell Biology

Senescence of alveolar stem cells drives progressive pulmonary fibrosis

C. Yao, X. Guan, G. Carraro, T. Parimon, X. Liu, G. Huang, H. Soukiasian, G. David, S. S. Weight, J. A. Belperio, P. Chen, D. Jiang, P. W. Noble, B. R. Stripp

This study shows that senescence of alveolar type 2 stem cells drives pulmonary fibrosis and that targeting p53 or Tgfβ can block fibrogenesis.

bioRxiv · Nov 18, 2019 · PreprintCell Biology