Bacterial pore-forming toxin pneumolysin drives pathogenicity through shed toxin-loaded host extracellular vesicles
S. Parveen, C. V. Bhat, S. Aziz, A. J, A. Dutta, S. Dutta, S. Show, K. Sharma, J. B. Johnson, U. Nongthomba, A. Banerjee, K. Subramanian
This study shows that pneumolysin-loaded host extracellular vesicles contribute to pneumococcal pathogenesis by inducing cytotoxicity and inflammation.
bioRxiv · Oct 12, 2023Microbiology