Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.
c. Traughber, G. deshpande, k. neupane, M. Khan, M. R. McMullen, S. Swaidani, E. Opoku, S. Muppals, J. Smith, L. Nagy, K. Gulshan
This study shows that GsdmD in myeloid cells promotes lung cancer metastasis in mice by enhancing inflammasome activity and IL-1β release.
bioRxiv · Aug 22, 2022Cancer Biology