Active zone protein SYD-2/Liprin-α acts downstream of LRK-1/LRRK2 to regulate polarized trafficking of synaptic vesicle precursors through clathrin adaptor protein complexes
S. S. P. Nadiminti, S. B. Dixit, N. Ratnakaran, S. Hegde, S. Swords, B. D. Grant, S. P. Koushika
This study identifies SYD-2/Liprin-α as a downstream effector of LRK-1/LRRK2 that regulates polarized trafficking of synaptic vesicle precursors through AP-3 and AP-1 complexes in C. elegans neurons.
bioRxiv · Feb 26, 2023 · PreprintCell Biology