The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module
S. T. Haile, S. Rahman, B. Orsburn, N. N. Bumpus, C. Wolberger
This study shows the SWIRM domain of Ada2 tethers the HAT module to SAGA, modulating its deubiquitinating activity.
bioRxiv · Dec 29, 2022Biochemistry