Author

S. T. Whitten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 4 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:protein sequence· 2

Frequent Co-Authors

L. E. Hough· 4 shared N. C. Fitzkee· 3 shared J. J. Correia· 2 shared K. A. Lewis· 2 shared A. B. Herr· 1 shared A. E. Yarawsky· 1 shared A. Erbse· 1 shared A. L. Ori· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersBiophysics

L. E. Hough

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Author profile →

5 papers

Recent·Most cited

Aggregation of an FG nucleoporin under crowded conditions

L. Maguire, S. Reskin, K. P. Wall, E. Arroyo, P. Marchando, A. M. Whited, A. Erbse, S. T. Whitten, L. E. Hough

This study examines how different crowding agents affect the aggregation of an FG nucleoporin peptide, revealing variations in kinetics and residue microenvironment.

bioRxiv · Apr 15, 2024 · PreprintBiophysics

ParSe 2.0: A web application that enables proteome-scale searches for sequences that drive protein-mediated phase separation

C. Wilson, K. A. Lewis, N. C. Fitzkee, L. E. Hough, S. T. Whitten

ParSe 2.0 predicts protein regions that drive phase separation using sequence-based descriptors and is available as a web application.

bioRxiv · Jun 20, 2023Biophysics

Convergent behavior of extended stalk regions from staphylococcal surface proteins with widely divergent sequence patterns

A. E. Yarawsky, A. L. Ori, L. R. English, S. T. Whitten, A. B. Herr

This study shows that stalk regions from different staphylococcal CWA proteins resist compaction and adopt extended conformations, despite sequence divergence.

bioRxiv · Jan 6, 2023Biophysics

Intrinsically disordered regions that drive phase separation form a robustly distinct protein class

A. Y. Ibrahim, N. P. Khaodeuanepheng, D. L. Amarasekara, J. J. Correia, K. A. Lewis, N. C. Fitzkee, L. E. Hough, S. T. Whitten

The paper identifies amino acid property scales that distinguish phase-separating intrinsically disordered regions from other protein regions and improves a predictor for these regions.

bioRxiv · Aug 4, 2022Biophysics

Beta Turn Propensity and a Model Polymer Scaling Exponent Identify Disordered Proteins that Phase Separate

E. A. Paiz, J. H. Allen, J. J. Correia, N. C. Fitzkee, L. E. Hough, S. T. Whitten

The paper identifies disordered proteins that phase separate by analyzing their polymer scaling exponent and beta-turn propensity, introducing a new algorithm, ParSe.

Journal of Biological Chemistry · Nov 1, 2021Peer-reviewedBiophysics