Author

K. A. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biophysics· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Approach:statistical model· 4 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2

Frequent Co-Authors

D. A. Hogan· 4 shared G. A. O'Toole· 3 shared J. de Anda· 3 shared G. C. L. Wong· 2 shared L. E. Hough· 2 shared N. C. Fitzkee· 2 shared S. Kuchma· 2 shared S. S. Webster· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersMicrobiology

D. A. Hogan

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

How individual P. aeruginosa cells with diverse stator distributions collectively form a heterogeneous macroscopic swarming population

J. de Anda, S. Kuchma, S. S. Webster, A. Boromand, K. A. Lewis, C. Lee, M. Contreras, V. F. Medeiros Pereira, D. A. Hogan, C. O'Hern, G. A. O'Toole, G. C. L. Wong

The paper shows that P. aeruginosa cells with different stator distributions create a heterogeneous swarming population through dynamic stator recruitment and motor intermittency.

mBio · Apr 10, 2024Peer-reviewedMicrobiology

ParSe 2.0: A web application that enables proteome-scale searches for sequences that drive protein-mediated phase separation

C. Wilson, K. A. Lewis, N. C. Fitzkee, L. E. Hough, S. T. Whitten

ParSe 2.0 predicts protein regions that drive phase separation using sequence-based descriptors and is available as a web application.

bioRxiv · Jun 20, 2023Biophysics

Intrinsically disordered regions that drive phase separation form a robustly distinct protein class

A. Y. Ibrahim, N. P. Khaodeuanepheng, D. L. Amarasekara, J. J. Correia, K. A. Lewis, N. C. Fitzkee, L. E. Hough, S. T. Whitten

The paper identifies amino acid property scales that distinguish phase-separating intrinsically disordered regions from other protein regions and improves a predictor for these regions.

bioRxiv · Aug 4, 2022Biophysics

Non-motile subpopulations of Pseudomonas aeruginosa repress flagellar motility in motile cells through a type IV pili- and Pel-dependent mechanism

K. A. Lewis, D. M. Vermilyea, S. S. Webster, C. J. Geiger, J. de Anda, G. Wong, G. A. O'Toole, D. A. Hogan

The paper shows non-motile Pseudomonas aeruginosa cells repress swarming motility in motile cells via type IV pili and Pel exopolysaccharide.

bioRxiv · Oct 21, 2021 · PreprintMicrobiology

Outbreeding depression as a selective force on mixed mating in the mangrove rivulus fish, Kryptolebias marmoratus

J. D. Gresham, K. A. Lewis, S. P. Summers, P. E. Gresham, R. L. Earley

This study investigates the effects of variable heterozygosity on survival, fecundity, and body condition in the mangrove rivulus fish under different salinity and water availability conditions, finding outbreeding depression.

bioRxiv · Feb 22, 2021 · PreprintEvolutionary Biology

Phenotypic differences in reversible attachment behavior reveal distinct P. aeruginosa surface colonization strategies

C. K.-m. Lee, J. Vachier, J. de Anda, k. zhao, A. Baker, R. R. Bennett, C. R. Armbruster, K. A. Lewis, R. L. Tarnopol, C. J. Lomba, D. A. Hogan, M. R. Parsek, G. A. O'Toole, R. Golestanian, G. C. L. Wong

The paper examines reversible attachment behavior in P. aeruginosa strains PAO1 and PA14, revealing distinct surface colonization strategies through single-cell tracking and stochastic modeling.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Ethanol decreases Pseudomonas aeruginosa flagellar motility through a cyclic-di-GMP- and stator-dependent pathway

K. A. Lewis, A. E. Baker, A. I. Chen, C. E. Harty, S. Kuchma, G. O'Toole, D. A. Hogan

This study shows ethanol reduces Pseudomonas aeruginosa motility by increasing c-di-GMP and involving stator and PilMNOP proteins.

bioRxiv · Sep 29, 2018Microbiology