Cancer BiologybioRxiv
Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini
S. Chaiyadet, S. Tangkawattana, M. J. Smout…·T. Laha
This study shows that knocking out the liver fluke gene Ov-grn-1 reduces malignant transformation in a hamster model of opisthorchiasis-associated cholangiocarcinoma.
DOI 10.1371/journal.ppat.1010839