Author

J. Sotillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Loukas· 6 shared G. G. Mekonnen· 2 shared L. Becker· 2 shared M. S. Pearson· 2 shared A. Amoah· 1 shared A. Thinkhamrop Suwannatrai· 1 shared A. Waardenberg· 1 shared B. A. Rosa· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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6 shared papersMicrobiology

A. Loukas

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Small extracellular vesicles but not microvesicles from Opisthorchis viverrini promote cell proliferation in human cholangiocytes.

S. Chaiyadet, J. Sotillo, M. Smout, M. Cooper, D. Doolan, A. Waardenberg, R. Eichenberger, M. A. Field, T. Laha, A. Loukas

This study identifies that specific extracellular vesicles from Opisthorchis viverrini promote human cholangiocyte proliferation, suggesting a role in cholangiocarcinoma development.

bioRxiv · May 22, 2023 · PreprintMicrobiology

Differential excretory/secretory proteome of the adult female and male stages of the human blood fluke, Schistosoma mansoni

E. T. Kenney, V. H. Mann, W. I. Tanno, B. A. Rosa, M. Mitreva, B. K. Bracken, A. Loukas, P. J. Brindley, J. Sotillo

The paper identifies and compares excretory/secretory proteins from adult male and female Schistosoma mansoni worms using proteomics, revealing sex-specific functional differences.

bioRxiv · May 22, 2022Microbiology

Schistosoma haematobium extracellular vesicle proteins confer protection in a heterologous model of schistosomiasis

G. G. Mekonnen, B. A. Tedla, D. Pickering, L. Becker, L. Wang, B. Zhan, M. E. Bottazzi, A. Loukas, J. Sotillo, M. S. Pearson

The paper identifies extracellular vesicle proteins from Schistosoma haematobium and shows that vaccinating mice with recombinant tetraspanins reduces egg burdens in a heterologous schistosomiasis model.

Vaccines · Jul 24, 2020Peer-reviewedMicrobiology

Hemocyte subpopulation changes in Bithynia snails infected with Opisthorchis viverrini in Thailand.

K. Suwannatrai, A. Thinkhamrop Suwannatrai, C. Donthaisong, P. Arunsan, K. Thinkhamrop, P. Tabsripair, J. U. Welbat, S. Tangkawattana, J. Sotillo, S. Tesana

This study examines changes in hemocyte subpopulations in three Bithynia snail species infected with Opisthorchis viverrini, showing differential immune responses over time.

bioRxiv · Feb 2, 2019 · PreprintImmunology

In-depth proteomic characterization of Schistosoma haematobium: towards the development of new tools for elimination

J. Sotillo, M. S. Pearson, L. Becker, G. G. Mekonnen, A. Amoah, G. van Dam, P. L. A. M. Corstjens, T. Mduluza, F. Mutapi, A. Loukas

This study characterizes the proteomes of Schistosoma haematobium and identifies potential diagnostic markers for infection intensity.

bioRxiv · Dec 10, 2018Microbiology

Characterisation Of Trichuris muris Secreted Proteins And Extracellular Vesicles Provides New Insights Into Host-Parasite Communication

R. M. Eichenberger, M. H. Talukder, M. Field, P. Wangchuk, P. Giacomin, A. Loukas, J. Sotillo

This study characterizes secreted proteins and extracellular vesicles from Trichuris muris, identifying their proteomic and genomic content and demonstrating their interaction with host cells.

bioRxiv · Dec 14, 2017Microbiology

Revisiting The Ancylostoma caninum Secretome Provides New Information On Hookworm-Host Interactions

T. Morante, C. Shepherd, C. Constantinoiu, A. Loukas, J. Sotillo

This study reanalyzes the secretome of Ancylostoma caninum using advanced techniques, identifying 315 proteins and highlighting potential vaccine candidates and immunomodulatory proteins.

bioRxiv · May 17, 2017Microbiology