Author

S. Udutha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Gillespie· 2 shared C. Taglang· 2 shared G. Batsios· 2 shared P. Viswanath· 2 shared B. Lau· 1 shared C. Koschmann· 1 shared J. ten Hoeve· 1 shared M. Tran· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. M. Gillespie

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2 papers

Recent·Most cited

GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas

G. Batsios, S. Udutha, C. Taglang, A. M. Gillespie, B. Lau, S. Ji, T. Phoenix, S. Mueller, S. Venneti, C. Koschmann, P. Viswanath

This study shows imipridones induce GABA accumulation in diffuse midline gliomas, which can be used for non-invasive imaging and therapy.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas

S. Udutha, C. Taglang, G. Batsios, A. M. Gillespie, M. Tran, S. M. Ronen, J. ten Hoeve, T. G. Graeber, P. Viswanath

This study identifies metabolic vulnerabilities in glioblastomas driven by TERT and shows that combining GCLC and glutamine-utilizing enzyme inhibitors synergistically targets these vulnerabilities.

bioRxiv · Nov 14, 2023 · PreprintCancer Biology