Autophagy functions in lung macrophages and dendritic cells to regulate allergen-dependent inflammatory responses
N. Dubey, R. Woodson, S. V. Hendrix, A. L. Rosen, R. L. Kinsella, S. R. McKee, M. Starick, N. Rivera-Espinal, S. K. Naik, A. Smirnov, D. Kreamalmeyer, A. L. Kau, C. L. Stallings
This study identifies autophagy's role in lung macrophages and dendritic cells in suppressing TH17 responses and neutrophil accumulation in allergic inflammation, with allergen-dependent effects on TH2 responses and cytokine secretion.
bioRxiv · Mar 16, 2023Immunology