Author

S. V. Khoronenkova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. J. Talbot· 1 shared E. Talbot· 1 shared J. Bourseguin· 1 shared K. Tsafou· 1 shared L. Hardy· 1 shared L. Joshi· 1 shared M. Dezfouli· 1 shared M. Perkinton· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

E. J. Talbot

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2 papers

Recent·Most cited

The cGAS-STING pathway regulates microglial chemotaxis in genome instability

E. J. Talbot, L. Joshi, P. Thornton, M. Dezfouli, K. Tsafou, M. Perkinton, S. V. Khoronenkova

This study shows that the cGAS-STING pathway drives microglial chemotaxis and inflammation in response to DNA damage, linking genome instability to neuroinflammation.

bioRxiv · Aug 25, 2023Cell Biology

Persistent DNA damage promotes microglial dysfunction in Ataxia-telangiectasia

J. Bourseguin, W. Cheng, E. Talbot, L. Hardy, S. V. Khoronenkova

This study shows that DNA damage in Ataxia-telangiectasia leads to microglial dysfunction via the RELB/p52 pathway, causing excessive neurite phagocytosis and contributing to neurodegeneration.

bioRxiv · Jun 2, 2021Cell Biology