Author

K. Tsafou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Gupta· 1 shared B. Gyorffy· 1 shared C. Behan· 1 shared C. Fagre· 1 shared C. Francavilla· 1 shared C. O'Brien· 1 shared D. Barden· 1 shared D. Lefley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Gupta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Proteomics Identifies Osteomodulin as a Promoter of Breast Cancer Bone Metastasis via CDK1 Activation

S. Cabral, J. Parsons, H. Harrison, T. Kedward, P. Fullwood, K. Spence, D. Lefley, D. Barden, J. Haworth, J. Watson, K. Tsafou, C. Behan, M. J. Dunning, N. Ali, B. Gyorffy, , R. Clarke

The paper identifies osteomodulin as a promoter of breast cancer bone metastasis through CDK1 activation using proteomics and phosphoproteomics analysis of patient-derived tumors.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology

The cGAS-STING pathway regulates microglial chemotaxis in genome instability

E. J. Talbot, L. Joshi, P. Thornton, M. Dezfouli, K. Tsafou, M. Perkinton, S. V. Khoronenkova

This study shows that the cGAS-STING pathway drives microglial chemotaxis and inflammation in response to DNA damage, linking genome instability to neuroinflammation.

bioRxiv · Aug 25, 2023Cell Biology

Using protein interaction networks to identify cancer dependencies from tumor genome data

H. Horn, C. Fagre, A. Gupta, K. Tsafou, N. Fornelos, J. T. Neal, K. Lage

This paper develops an algorithm to predict cancer dependencies from tumor genomes by analyzing protein interaction networks and validates its predictions using CRISPR screens.

bioRxiv · Aug 27, 2020 · PreprintCancer Biology