S. V. Singh

Medulloblastoma-associated DDX3X mutants are oncogenic having a defect in translation-promoting activity but functional in stress granule formation and interferon signaling

This study shows that DDX3X mutations in medulloblastoma impair translation-promoting activity but retain function in stress granules and interferon signaling, suggesting helicase activity as a tumor suppressor.

Novel mechanistic targets of Forkhead box Q1 transcription factor in human breast cancer cells

This study identifies novel mechanistic targets of FoxQ1 in human breast cancer cells using RNA-seq and chromatin immunoprecipitation, revealing its role in regulating IL-1, IL-8, and VEGF.

Inhibitor of sarco/endoplasmic reticulum calcium-ATPase impairs paramyxovirus replication

This study shows that SERCA inhibition reduces paramyxovirus replication and that viruses can develop resistance to this inhibition.