Breathing on Chip: Dynamic flow and stretch tune cellular composition and accelerate mucociliary maturation of airway epithelium in vitro
J. C. Nawroth, D. Roth, A. van Schadewijk, A. Ravi, T. I. Maulana, C. N. Senger, S. van Riet, D. K. Ninaber, D. Kraft, P. S. Hiemstra, A. L. Ryan, A. M. van der Does
This study shows that applying airflow and stretch to airway epithelial cultures on a chip accelerates mucociliary maturation and alters cellular composition to better mimic airway biology.
bioRxiv · May 7, 2021 · PreprintCell Biology