BiochemistrybioRxiv
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
F. Adolf, J. Du, E. A. Goodall…·B. A. Schulman
The paper uses cryo-EM to visualize the assembly of the human 20S proteasome, revealing how chaperones and propeptides guide subunit incorporation and proteasome activation.