Respiration enhances TDP-43 toxicity, but TDP-43 retains some toxicity in the absence of respiration
S.-K. Park, S. Park, S. W. Liebman
This paper shows that TDP-43 is more toxic in yeast under respiratory conditions but remains toxic without respiration, suggesting reactive oxygen species may enhance its toxicity.
bioRxiv · Mar 8, 2019Cell Biology