Author

S. X. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Dakhovnik· 1 shared A. Feit· 1 shared C. Cai· 1 shared C. Statzer· 1 shared C. Y. Ewald· 1 shared C.-H. Chen· 1 shared E. Jongsma· 1 shared F. Wandrey· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Dakhovnik

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2 papers

Recent·Most cited

Youthful and age-related matreotypes predict drugs promoting longevity

C. Statzer, E. Jongsma, S. X. Liu, A. Dakhovnik, F. Wandrey, P. Mozharovskyi, F. Zuelli, C. Y. Ewald

The paper identifies drugs that promote longevity by screening for compounds that alter extracellular matrix gene expression and validate them using a collagen-based longevity surrogate marker in C. elegans.

bioRxiv · Jan 26, 2021Pharmacology & Toxicology

A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress

Y. LIAO, C.-H. Chen, N. Shah, T. Xiao, A. Feit, M. Yang, C. Cai, S. Gao, P. Xue, Z. Liu, H. Xu, J. Lee, W. Li, S. Mei, R. S. Pierre, , K. Xu

This study shows EZH2 inhibitors inhibit CRPC growth by downregulating DNA repair genes, making cancer cells more sensitive to genotoxic stress.

bioRxiv · Sep 11, 2020 · PreprintCancer Biology