Author

S. Yasa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Sauvageau· 2 shared G. Modica· 2 shared S. Lefrancois· 2 shared A. Kaleem· 1 shared C. T. Ford· 1 shared D. A. Janies· 1 shared D. T. Jacob Machado· 1 shared G. Hermey· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

E. Sauvageau

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Predicting changes in neutralizing antibody activity for SARS-CoV-2 XBB.1.5 using in silico protein modeling

C. T. Ford, S. Yasa, D. T. Jacob Machado, R. A. White, D. A. Janies

The paper predicts the impact of XBB.1.5 mutations on neutralizing antibody activity using in silico protein modeling, finding no significant overall evasion but noting specific affinity changes.

bioRxiv · Feb 10, 2023Biochemistry

CLN5 and CLN3 function as a complex to regulate endolysosome function

S. Yasa, E. Sauvageau, G. Modica, S. Lefrancois

This paper shows that CLN5 and CLN3 form a complex that regulates endolysosome function by modulating retromer and Rab7A interactions, affecting endocytic protein degradation and autophagy.

bioRxiv · Dec 24, 2020Cell Biology

CLN3 regulates endosomal function by modulating Rab7A activity

S. Yasa, G. Modica, E. Sauvageau, A. Kaleem, G. Hermey, S. Lefrancois

This study identifies CLN3's role in regulating Rab7A activity to control endosomal trafficking and autophagy, explaining JNCL pathogenesis.

bioRxiv · May 10, 2019 · PreprintCell Biology