PhysiologybioRxivPreprint
Immunomodulatory Leptin Receptor+ Sympathetic Perineurial Cells Protect Against Obesity by Facilitating Neuroendocrine-Mediated Brown Adipose Tissue Thermogenesis
E. R. Haberman, G. Sarker, B. A. Arus…·A. I. Domingos
This paper identifies leptin receptor-expressing sympathetic perineurial cells that produce IL33, which prevents BAT inflammation and obesity by supporting thermogenesis and immune regulation.
DOI 10.1101/2023.05.09.539963