Author

A. I. Domingos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. J. O. O'Brien· 3 shared C. A. P. Sweeney· 2 shared E. R. Haberman· 2 shared G. Ratti· 2 shared S. Gordon· 2 shared A. Raimondi· 1 shared A. Stawiarski· 1 shared B. A. Arus· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

C. J. O. O'Brien

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Class A Scavenger Receptor MARCO negatively regulates Ace expression and aldosterone production

C. J. O. O'Brien, G. Ratti, H. Veida-Silva, E. R. Haberman, C. A. P. Sweeney, S. Gordon, A. I. Domingos

The paper shows that MARCO on alveolar macrophages reduces Ace expression and aldosterone production in male mice lungs.

bioRxiv · Sep 26, 2023Immunology

Distinct adrenal gland macrophages regulate corticosteroid production

C. J. O. O'Brien, D. Sidarta-Oliveira, A. Stawiarski, G. Ratti, P.-L. Loyher, M. Makhlouf, E. H. AbouMoussa, E. Haberman, C. A. P. Sweeney, Y. Mizuno, T. Ishii, T. Hasegawa, E. P. Gomez-Sanchez, C. E. Gomez-Sanchez, S. Gordon, , A. I. Domingos

This study identifies two distinct adrenal macrophage subsets in mice and shows that foamy macrophages regulate corticosteroid production through cholesterol accumulation.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Immunomodulatory Leptin Receptor+ Sympathetic Perineurial Cells Protect Against Obesity by Facilitating Neuroendocrine-Mediated Brown Adipose Tissue Thermogenesis

E. R. Haberman, G. Sarker, B. A. Arus, S. Yilmaz-Ozcan, N. Martinez-Sanchez, E. Freibergerova, I. Fernandez-Gonzalez, C. Zentai, C. J. O. O'Brien, D. E. Grainger, S. Chakarov, A. Raimondi, M. Iannacone, M. Lopez, F. Ginhoux, A. I. Domingos

This paper identifies leptin receptor-expressing sympathetic perineurial cells that produce IL33, which prevents BAT inflammation and obesity by supporting thermogenesis and immune regulation.

bioRxiv · May 9, 2023 · PreprintPhysiology