Bacterial retrons enable precise gene editing in human cells
B. Zhao, S.-A. A. Chen, J. Lee, H. B. Fraser
This study shows retrons can generate donor DNA for HDR gene editing in human cells, achieving up to 11.3% HDR efficiency when combined with CRISPR-Cas9.
The CRISPR Journal · Feb 22, 2022Peer-reviewedBioengineering