RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction point
J. Lee, D. Kim, J. Jang, T. Park, Y. Lee, X.-Z. Chi, I. Y. Park, J. Hyun, Y. Ito, S.-C. Bae
This study shows RUNX3 regulates chromatin dynamics at the restriction point by opening and closing target loci through recruitment of chromatin modifiers, influencing cell cycle progression and tumor development.
bioRxiv · Sep 7, 2018Cell Biology