Broad neutralizing nanobody against SARS-CoV-2 engineered from pre-designed synthetic library
Q. Liu, C. Cai, Y. Huang, L. Zhou, Y. Guan, S. Fu, Y. Lin, T. Yang, X. Liang, N. Wang, F. Zhang, Q. Sun, Y. Bai, Y. Chen, H. Yan, , Y. Xiong
The paper reports the discovery of a neutralizing nanobody, VHH60, effective against SARS-CoV-2 and its variants, with high potency and protective efficacy in mice.
bioRxiv · Aug 7, 2021 · PreprintMicrobiology