Structural characterization of a pathogenic antibody underlying vaccine-induced immune thrombotic thrombocytopenia (VITT)
S. N. Nguyen, S.-H. Le, D. G. Ivanov, N. Ivetic, I. Nazy, I. A. Kaltashov
This paper characterizes a pathogenic anti-PF4 antibody from VITT patients, revealing its monoclonal nature, N-glycosylation site, and subclass composition.
bioRxiv · May 28, 2023Biochemistry