Author

Y. Izumi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

T. Bamba· 3 shared K. Furuse· 2 shared M. Furuse· 2 shared M. Takahashi· 2 shared A. Harned· 1 shared A. Kishino· 1 shared A. Vandenbon· 1 shared C. He· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

T. Bamba

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Low albumin status accompanies multi-layered immunosuppressive phenotypes in metastatic breast cancer patients

Y. Nakamura, M. Yoda, Y. Izumi, Y. Kashima, M. Takahashi, K. Nakatani, T. Bamba, C. He, R. Konishi, D. P. Saldajeno, A. Vandenbon, Y. Suzuki, M. Toi, K. Kawaguchi, S. Kawaoka

The paper investigates the association between low albumin levels and immunosuppressive phenotypes in metastatic breast cancer patients using transcriptomic and metabolomic data.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology

PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity

H. Sekine, H. Takeda, A. Kishino, H. Anzawa, T. Isagawa, N. Ota, N. Kato, S. Kimura, Z. Liu, K. Kato, F. Katsuoka, M. Yamamoto, F. Miura, T. Ito, M. Takahashi, , H. Motohashi

The paper identifies the PNPO-PLP axis as a mechanism for sensing prolonged hypoxia by regulating lysosomal activity in macrophages, leading to altered inflammatory responses.

bioRxiv · Oct 28, 2022 · PreprintBiochemistry

Endosomes deliver ceramide phosphoethanolamine with unique acyl chain anchors to the cleavage furrow during male meiotic cytokinesis

G. Kunduri, S.-H. Le, V. Baena, V. Nagampalli, A. Harned, K. Nagashima, D. Blankenberg, Y. Izumi, K. Narayan, T. Bamba, U. Acharya, J. K. Acharya

This study identifies Ceramide phosphoethanolamine (CPE) and its delivery via Rab7-positive endosomes as essential for male meiotic cytokinesis.

bioRxiv · Apr 27, 2021Cell Biology

A novel membrane protein Hoka regulates septate junction organization and stem cell homeostasis in the Drosophila gut

Y. Izumi, K. Furuse, M. Furuse

bioRxiv · Nov 10, 2020Cell Biology

Erythropoietin production?by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation

Y. Yasuoka, T. Fukuyama, Y. Izumi, Y. Nakayama, H. Inoue, K. Yanagita, T. Oshima, T. Yamazaki, T. Uematsu, N. Kobayashi, Y. Shimada, Y. Nagaba, M. Mukoyama, T. Yamashita, Y. Sato, , H. Nonoguchi

This study develops a Western blot method with deglycosylation to detect Epo and ESAs in urine and plasma, showing the kidney as the main site of Epo production under hypoxia.

bioRxiv · Mar 11, 2020Physiology

Septate junctions regulate gut homeostasis through regulation of stem cell proliferation and enterocyte behavior in Drosophila

Y. Izumi, K. Furuse, M. Furuse

The paper shows that depletion of septate junction proteins in Drosophila adult midgut enterocytes causes intestinal hypertrophy, abnormal enterocytes, and increased stem cell proliferation.

bioRxiv · Mar 19, 2019Cell Biology