Author
S.-H. Shiu
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2017-2023 · peak 6/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author links14 papers
Recent·Most cited
Temporal Regulation of Cold Transcriptional Response in Switchgrass
T. Ranaweera, B. N. I. Brown, P. Wang, S.-H. Shiu
The paper identifies cis-regulatory elements in switchgrass that regulate cold-responsive gene expression over time using machine learning on transcriptome data.
bioRxiv · Aug 1, 2022 · PreprintPlant Biology
Genome-wide predictions of genetic redundancy in Arabidopsis thaliana
S. A. Cusack, P. Wang, B. M. Moore, F. Meng, J. K. Conner, P. J. Krysan, M. D. Lehti-Shiu, S.-H. Shiu
This study develops a machine learning model to predict genetic redundancy in Arabidopsis thaliana using diverse features, identifying key predictors like recent duplication and stress-related expression.
bioRxiv · Aug 13, 2020 · PreprintEvolutionary Biology
Modeling gene regulation in response to wounding: temporal variations, hormonal variations, and specialized metabolism pathways induced by wounding
B. M. Moore, Y. S. Lee, E. Grotewold, S.-H. Shiu
The paper models gene regulation in plants after wounding using machine learning, identifying cis-regulatory elements and showing their role in temporal and hormonal responses.
bioRxiv · Jul 15, 2020 · PreprintPlant Biology
Optimizing the use of gene expression data to predict plant metabolic pathway memberships
P. Wang, B. M. Moore, S. Uygun, M. D. Lehti-Shiu, C. Barry, S.-H. Shiu
This study predicts plant metabolic pathway memberships using gene expression data and machine learning, finding that unsupervised learning and expression similarity outperform naive methods in some cases.
bioRxiv · Jul 15, 2020Plant Biology
Evolutionary analysis of the LORELEI gene family in angiosperms reveals regulatory subfunctionalization
J. A. Noble, N. V. Bielski, M.-C. J. Liu, T. A. DeFalco, M. Stegmann, A. D. L. Nelson, K. McNamara, B. Sullivan, K. K. Dinh, N. Khuu, S. Hancock, S.-H. Shiu, C. Zipfel, A. Y. Cheung, M. A. Beilstein, R. Palanivelu
The paper investigates LLG gene family evolution in angiosperms and finds expression divergence, not functional divergence, explains retention of paralogs in Brassicales.
bioRxiv · Apr 27, 2020Plant Biology
Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity
P. Fan, P. Wang, Y.-R. Lou, B. J. Leong, B. J. Moore, C. A. Schenck, R. Combs, P. Cao, F. Brandizzi, S.-H. Shiu, R. L. Last
The paper studies the evolution of a gene cluster in Solanaceae plants and its role in producing medium chain acylsugars through trichome-specific enzymes.
bioRxiv · Mar 4, 2020Plant Biology
Within and cross species predictions of plant specialized metabolism genes using transfer learning
B. M. Moore, P. Wang, P. Fan, A. Lee, B. Leong, Y.-L. Lou, C. A. Schenck, K. Sugimoto, R. Last, M. D. Lehti-Shiu, C. Barry, S.-H. Shiu
The paper uses transfer learning to predict specialized metabolism genes in tomato by leveraging annotations from Arabidopsis thaliana, improving prediction accuracy.
bioRxiv · Jan 13, 2020Plant Biology
Putative cis-regulatory elements predict iron deficiency responses in Arabidopsis roots
B. Schwarz, C. B. Azodi, S.-H. Shiu, P. Bauer
The paper identifies 100 putative cis-regulatory elements that predict Arabidopsis root responses to iron deficiency using computational analysis of genome and transcriptome data.
bioRxiv · Apr 11, 2019Plant Biology
Cis-regulatory code for predicting plant cell-type specific high salinity response
S. Uygun, C. B. Azodi, S.-H. Shiu
The paper identifies cis-regulatory elements in Arabidopsis root cell types that predict high salinity gene responses and shows their effectiveness compared to in vitro transcription factor data.
bioRxiv · Nov 8, 2018Plant Biology
Robust predictions of specialized metabolism genes through machine learning
B. M. Moore, P. Wang, P. Fan, B. Leong, C. A. Schenck, J. P. Lloyd, M. Lehti-Shiu, R. Last, E. Pichersky, S.-H. Shiu
The paper develops a machine learning model to predict specialized metabolism genes in Arabidopsis thaliana by integrating multiple genomic features, achieving high accuracy in identification.
bioRxiv · Oct 15, 2018Plant Biology
Factors influencing gene family size variation among related species in a plant family
P. Wang, B. M. Moore, N. L. Panchy, F. Meng, M. D. Lehti-Shiu, S.-H. Shiu
The paper investigates gene family size variation in Solanaceae species, finding relationships between gene function, duplication mechanisms, and evolutionary rates.
bioRxiv · Feb 23, 2018Evolutionary Biology
Regulatory Divergence In Wound-Responsive Gene Expression In Domesticated And Wild Tomato
M.-J. Liu, K. Sugimoto, S. Uygun, N. Panchy, M. S. Campbell, M. Yandell, G. A. Howe, S.-H. Shiu
This study identifies cis- and trans-regulatory divergence in wound-responsive gene expression between wild and domesticated tomato species.
bioRxiv · Apr 4, 2017Evolutionary Biology