P. Fan

Nitric Oxide controls shoot meristem activity via regulation of DNA methylation

This study shows that nitric oxide regulates DNA methylation in Arabidopsis shoot meristems by modulating AGO4 activity and its interaction with the WUSCHEL transcription factor.

Phylogenomics reveals incomplete lineage sorting and ancient hybrid drove the radiation of macaques

This study uses phylogenomic analysis of macaque genomes to show that incomplete lineage sorting and ancient hybridization contributed to the radiation of macaques.

A plant virus causes symptoms through the deployment of a host-mimicking protein domain to attract the insect vector

This study identifies how the tomato yellow leaf curl virus uses a host-mimicking protein domain to disrupt plant processes and attract insect vectors, facilitating viral spread.

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

Effects of Guangzhou seasonal climate change on the development of Aedes albopictus and its susceptibility to DENV-2

This study examines how seasonal climate changes in Guangzhou affect Aedes albopictus development and its susceptibility to DENV-2, finding that mosquitoes can still transmit the virus in winter.

Combinatorial interactions between viral proteins expand the functional landscape of the viral proteome

This study shows that viral proteins interact combinatorially, leading to new biological functions beyond their individual roles during infection.

Thinopyrum intermedium TiAP1 interacts with a chitin deacetylase from Blumeria graminis f. sp. tritici and increases the resistance to Bgt in wheat

This study identifies TiAP1 from Thinopyrum intermedium as a resistance gene against Blumeria graminis f. sp. tritici, showing it interacts with BgtCDA1 and enhances wheat resistance through immune activation.

A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability

This paper identifies a potent neutralizing antibody targeting the N-terminal domain of SARS-CoV-2 Spike protein, revealing it as a new therapeutic target.

Targeted genome editing in Nicotiana tabacum using inducible CRISPR/Cas9 system

This study develops an estrogen-inducible CRISPR/Cas9 system in Nicotiana tabacum and demonstrates its efficacy in inducing targeted mutagenesis of the NtPDS gene.

Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity

The paper studies the evolution of a gene cluster in Solanaceae plants and its role in producing medium chain acylsugars through trichome-specific enzymes.

Within and cross species predictions of plant specialized metabolism genes using transfer learning

The paper uses transfer learning to predict specialized metabolism genes in tomato by leveraging annotations from Arabidopsis thaliana, improving prediction accuracy.

The receptor-like kinases BAM1 and BAM2 promote the cell-to-cell movement of miRNA in the root stele to regulate xylem patterning

The paper shows BAM1 and BAM2 kinases facilitate miR165/6 movement through plasmodesmata, regulating xylem patterning in the root.

Evolution of metabolic novelty: a trichome-expressed invertase creates specialized metabolic diversity in wild tomato

The paper identifies a trichome-expressed invertase in wild tomato that converts acylsucroses into acylglucoses, enabling specialized metabolic diversity.

Robust predictions of specialized metabolism genes through machine learning

The paper develops a machine learning model to predict specialized metabolism genes in Arabidopsis thaliana by integrating multiple genomic features, achieving high accuracy in identification.

A plant receptor-like kinase promotes cell-to-cell spread of RNAi and is targeted by a virus

The paper identifies BAM1 as a positive regulator of RNAi cell-to-cell spread and shows that a viral protein inhibits this process by interacting with BAM1 and BAM2.