Author

Y. S. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Gopalan· 1 shared B. Han· 1 shared B. M. Moore· 1 shared B. S. Carver· 1 shared B. Y. Park· 1 shared C. J. Ballard· 1 shared C. M. Khoo· 1 shared C. N. Jayasena· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperCancer Biology

A. Gopalan

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Author profile →

7 papers

Recent·Most cited

Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility

S. Mowla, L. Farahani, T. Tharakan, R. Davies, G. D. Correia, Y. S. Lee, S. Kundu, S. Khanjani, E. Sindi, R. Rai, L. Regan, D. Khalifa, R. Henkel, S. Minhas, W. S. Dhillo, , C. N. Jayasena

This study compares semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility, finding no overall association but highlighting Flavobacterium's potential role.

bioRxiv · Feb 18, 2024Microbiology

A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is structurally and functionally distinct from host homologues

P. Kumar, T. Tomita, T. A. Gerken, C. J. Ballard, Y. S. Lee, L. M. Weiss, N. L. Samara

This study identifies and characterizes a Toxoplasma gondii O-glycosyltransferase, T.gondii-GalNAc-T3, revealing structural and functional differences from host homologues and identifying potential drug targets for parasitic diseases.

bioRxiv · Oct 26, 2023 · PreprintBiochemistry

Unbiased phosphoproteomics analysis unveils modulation of insulin signaling by extramitotic CDK1 kinase activity in human myotubes

B. Han, G. X. Li, W. L. Liew, E. Chan, S. Huang, C. M. Khoo, M. K.-S. Leow, Y. S. Lee, T. Zhao, L. C. Wang, R. M. Sobota, H. Choi, M. H. Liu, K. P. Kim, E. S. Tai

The paper uses phosphoproteomics to show that CDK1 activity modulates insulin signaling and glucose uptake in human myotubes, with group-specific phosphorylation changes observed.

bioRxiv · Jun 30, 2023 · PreprintPhysiology

ERG activates a stem-like proliferation-differentiation program in prostate epithelial cells with mixed basal-luminal identity

W. Feng, E. Ladewig, N. Salsabeel, H. Zhao, Y. S. Lee, A. Gopalan, M. Lange, H. Luo, W. Kang, N. Fan, E. Rosiek, E. De Stanchina, Y. Chen, B. S. Carver, C. S. Leslie, C. Sawyers

The paper identifies a stem-like proliferative state in prostate epithelial cells driven by ERG activation, which transitions to luminal cells and is associated with specific chromatin states.

bioRxiv · May 15, 2023Cancer Biology

Modeling gene regulation in response to wounding: temporal variations, hormonal variations, and specialized metabolism pathways induced by wounding

B. M. Moore, Y. S. Lee, E. Grotewold, S.-H. Shiu

The paper models gene regulation in plants after wounding using machine learning, identifying cis-regulatory elements and showing their role in temporal and hormonal responses.

bioRxiv · Jul 15, 2020 · PreprintPlant Biology

E prostanoid receptor 4 expressing macrophages promote the regeneration of the intestinal epithelial barrier upon inflammation

Y. R. Na, D. Jung, M. Stakenborg, G. J. Gu, M. R. Jeong, H. R. Jang, S. Y. Suh, H. J. Kim, Y. H. Kwon, T. S. Sung, S. B. Ryoo, K. J. Park, J. P. Im, J. Y. Park, Y. S. Lee, , S. H. Seok

The paper identifies EP4-expressing intestinal macrophages that promote mucosal healing by secreting CXCL1 during inflammation resolution.

bioRxiv · May 4, 2020Immunology

Measurements of three-dimensional refractive index tomography and membrane deformability of live erythrocytes from Pelophylax nigromaculatus

G. Kim, M. Lee, S. Youn, E. Lee, D. Kwon, J. Shin, S. Lee, Y. S. Lee, Y. Park

This study measures 3D refractive index and membrane properties of live erythrocytes from Pelophylax nigromaculatus to compare interspecific differences with mammals.

bioRxiv · Oct 20, 2017Biophysics