Author

S.-J. J. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:imputation· 2 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. Upadhyaya· 2 shared H. Sasaki· 2 shared H. Shroff· 2 shared J. CheniD· 2 shared M. Guo· 2 shared X. Li· 2 shared Y. Su· 2 shared Y. Wu· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. Upadhyaya

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3 papers

Recent·Most cited

Three-dimensional structured illumination microscopy with enhanced axial resolution

X. Li, Y. Wu, Y. Su, I. A. R. Suarez, C. Matthaeus, T. B. Updegrove, Z. Wei, L. Zhang, H. Sasaki, Y. Li, M. Guo, J. P. Giannini, H. D. Vishwasrao, J. Chen, S.-J. J. Lee, , H. Shroff

The paper introduces two methods to enhance axial resolution in 3D SIM microscopy, achieving isotropic resolution with minimal hardware changes and using deep learning for improved imaging.

Nature Biotechnology · Jan 26, 2023Peer-reviewedCell Biology

Three-dimensional residual channel attention networks denoise and sharpen fluorescence microscopy image volumes

J. Chen, H. Sasaki, H. Lai, Y. Su, J. Liu, Y. Wu, A. Zhovmer, C. A. Combs, I. Rey-Suarez, H. Chang, C. C. Huang, X. Li, M. Guo, S. Nizambad, A. Upadhyaya, , H. Shroff

This paper applies RCAN to enhance fluorescence microscopy image volumes, achieving denoising and resolution improvements across multiple microscopy techniques.

Nature Methods · May 31, 2021Peer-reviewedBioengineering

Fibrin Prestress Due to Platelet Aggregation and Contraction Increases Clot Stiffness

S. J. Pathare, W. Eng, S.-J. J. Lee, A. Ramasubramanian

This study shows platelet aggregation and contraction increase clot stiffness by inducing fibrin prestress and compaction.

bioRxiv · Apr 19, 2021Bioengineering